SODIUM-HYDROGEN EXCHANGER ISOFORM-1 INHIBITION: A PROMISING PHARMACOLOGICAL INTERVENTION FOR RESUSCITATION FROM CARDIAC ARREST

Sodium-Hydrogen Exchanger Isoform-1 Inhibition: A Promising Pharmacological Intervention for Resuscitation from Cardiac Arrest

Out-of-hospital sudden cardiac arrest is a major public health problem with an overall survival of less than 5%.Upon cardiac arrest, cessation of coronary blood flow rapidly leads to intense myocardial ischemia and activation of the sarcolemmal Na+-H+ exchanger isoform-1 (NHE-1).NHE-1 activation drives Na+ into cardiomyocytes in exchange for H+ wit

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Analysis of Bearing Safety and Influencing Factors of Supporting Structures of Hydraulic Tunnels in Cold Regions Based on Frost Heave

In order to study the bearing safety and influencing factors of the support structures of hydraulic tunnels in cold regions under the action of low-temperature frost heave, a mechanical model of the support structure and surrounding rock was established.Taking a hydraulic tunnel of a hydropower station in Xinjiang as the research object, a combinat

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